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上海信裕生物科技有限公司
H6PD抗体

H6PD抗体

商家询价

产品名称： H6PD抗体

英文名称： H6PDAntibody

产品编号： XY15255-1-

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 H6PD抗体

Applications
In-house applications ELISA, IHC, WB, IP     Application not tested? Please see our Guarantee.
Species specificity Human,Mouse,Rat; other species not tested.
Images
Prev12NextView more validation data
  • 15255-1-AP;human hepatocirrhosisImmunohistochemical of paraffin-embedded human hepatocirrhosis using 15255-1-AP(H6PD antibody) at dilution of 1:100 (under 10x lens)
  • 15255-1-AP;human hepatocirrhosisImmunohistochemical of paraffin-embedded human hepatocirrhosis using 15255-1-AP(H6PD antibody) at dilution of 1:100 (under 40x lens)
  • 15255-1-AP;HepG2 cellsHepG2 cells were subjected to SDS PAGE followed by western blot with 15255-1-AP( H6PD Antibody) at dilution of 1:1000
  • 15255-1-AP;HepG2 cellsIP Result of anti-H6PD (IP:15255-1-AP, 4ug; Detection:15255-1-AP 1:1000) with HepG2 cells lysate 1600ug.
Positive WB detected in HepG2 cells, HeLa cells, mouse liver tissue
Positive IP detected in HepG2 cells
Positive IHC detected in Human hepatocirrhosis tissue, human liver cancer tissue
Recommended dilution WB : 1:500-1:5000
IP : 1:500-1:5000
IHC : 1:20-1:200
 H6PD抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information H6PD抗体
Immunogen H6PD fusion protein ag7109 Full name Hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
Calculated molecular
weight		 89 kDa Observed molecular 
weight		 89-95 kDa
GenBank accession 
number		 BC081559 Gene ID (NCBI) 9563
Gene symbol H6PD Synonyms 6PGL, DKFZp686A01246, G6PDH, GDH, H6PD
Background

Hexose-6-phosphate dehydrogenase (H6PD) is also named as GDH,6PGL. It is the main NADPH generating enzyme in the lumen of the endoplasmic reticulum. H6PD is regarded as an ancillary enzyme in prereceptorial glucocorticoid activation and probably acts as a nutrient sensor and as a prosurvival factor(PMID:21620971). H6PD has been shown to be a glycoprotein and tissue differences in glycosylation status might explain both the difference in migration on SDS-PAGE gels as well as in activity. Defects in H6PD are a cause of cortisone reductase deficiency (CRD). This antibody is specific to H6PD. H6PD抗体

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