FZR1抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
FZR1抗体

FZR1抗体

商家询价

产品名称： FZR1抗体

英文名称： FZR1Antibody

产品编号： XY16368-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 FZR1抗体

Applications
In-house applications ELISA, WB, IP, IF     Application not tested? Please see our Guarantee.
Published applications WB Publications 1 citations –view here
Species specificity Human,Mouse,Rat; other species not tested.
Published Species Mouse
Images
Prev1NextView more validation data
  • 16368-1-AP;NIH/3T3 cellsNIH/3T3 cells were subjected to SDS PAGE followed by western blot with 16368-1-AP( FZR1 Antibody) at dilution of 1:600
  • 16368-1-AP;mouse heart tissueIP Result of anti-FZR1 (IP:16368-1-AP, 4ug; Detection:16368-1-AP 1:500) with mouse heart tissue lysate 3200ug.
  • 16368-1-AP;HeLa cellsImmunofluorescent analysis of ( 10% Formaldehyde ) fixed HeLa cells using 16368-1-AP( FZR1 Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Positive WB detected in NIH/3T3 cells, C6 cells, HeLa cells, HepG2 cells, Jurkat cells, mouse heart tissue, mouse liver tissue
Positive IP detected in Mouse heart tissue
Positive IF detected in HeLa cells
Recommended dilution WB : 1:200-1:2000
IP : 1:200-1:2000
IF : 1:50-1:500
 FZR1抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen FZR1 fusion protein ag9201 Full name Fizzy/cell division cycle 20 related 1 (Drosophila)
Calculated molecular
weight		 493aa,55 kDa Observed molecular 
weight		 55 kDa
GenBank accession 
number		 BC013413 Gene ID (NCBI) 51343
Gene symbol FZR1 Synonyms CDC20 like protein 1, CDC20C, CDH1, Cdh1/Hct1 homolog, Fizzy related protein homolog, FYR, FZR, FZR1, FZR2, HCDH, HCDH1, KIAA1242
Background FZR1抗体

FZR1 gene, also named as FYR, FZR and KIAA1242, has been previously shown to be mutated in lobular breast carcinomas. Direct evidence of FZR1 mutations triggering tumorigenesis has been investigated. FZR1 is a key regulator of ligase activity of the anaphase promoting complex/cyclosome (APC/C) which is playing vital role s in cell cycle progression. There are 7 WD-repeat domains in FZR1. Upon phosphorylation and dephosphorylation, it interacts with other components to modulate cell mitosis. This gene is different to E-cadherin (CDH1)which is an epithelial cell adhesion molecule. FZR1抗体

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